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A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women (mRNA Profiling)

ABSTRACT: The goal of this study is to identify aging-related biomarkers to improve our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases.

ORGANISM(S): Homo sapiens

PROVIDER: GSE49839 | GEO | 2013/08/13

SECONDARY ACCESSION(S): PRJNA215070

REPOSITORIES: GEO

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			Action	DRS
		Other
	GSE49839_RAW.tar	Raw
	GSE49839_mRNA_Illumina_Raw_Data.txt.gz	Txt
	filelist.txt	Txt

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Similar Datasets

A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women (MicroRNA Profiling)

2013-08-13 | GSE49837 | GEO

A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women (mRNA Profiling)

Project description:The goal of this study is to identify aging-related biomarkers to improve our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases. Global gene expression patterns from peripheral blood of two groups of healthy young adult women, among which 13 were aged 22-25 and 9 were aged 36-39 years old, were compared to determine changes in gene expression that are associated with aging.

2013-08-13 | E-GEOD-49839 | biostudies-arrayexpress

A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women (MicroRNA Profiling)

Project description:The goal of this study is to identify aging-related biomarkers to improve our understanding of complex physiological changes, thereby providing a means to investigate the mechanism by which aging influences various diseases. Global microRNA expression patterns from peripheral blood of two groups of healthy young adult women, among which 13 were aged 22-25 and 9 were aged 36-39 years old, were compared to determine changes in microRNA expression that are associated with aging.

2013-08-13 | E-GEOD-49837 | biostudies-arrayexpress

A Parallel Study of mRNA and microRNA Profiling of Peripheral Blood in Young Adult Women.

Project description: Not available

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A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women

Project description:This SuperSeries is composed of the SubSeries listed below.

2013-08-13 | GSE30205 | GEO

A Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2013-08-13 | E-GEOD-30205 | biostudies-arrayexpress

Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women

Project description:Breast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of poor-prognostic breast cancers. However, it is not known if antagonising progesterone can prevent breast cancers in humans. We suggest that targeting progesterone signalling could be a means of reducing features which are known to promote breast cancer formation.

2022-05-16 | GSE157126 | GEO

An mRNA Profiling Study of Vaginal Swabs from Pre- and Postmenopausal Women.

Project description: Not available

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RNA-seq profiling of epidermal tissues of visually younger and older women in the Youngster-Oldie (Y-O) study

Project description:Skin, with its distinctive features and visible signs of aging, provides a remarkable model for studying the aging process. The variable rate of skin aging among individuals provides a valuable opportunity to capture a wide range of age-related changes. In this study, we used bulk RNA sequencing (RNA-seq) to explore the diverse skin characteristics of individuals with both older and younger appearances.

2023-12-04 | GSE249225 | GEO

Global transcriptional profiling using RNA sequencing and DNA methylation patterns in highly enriched mesenchymal cells from young versus elderly women.

Project description:Purpose: Identification of relevant genetic pathways that are altered with aging knowing that the precursors for bone-forming osteoblasts reside in the mesenchymal cell population of bone marrow. Method: harvested and characterized, without in vitro culture, mesenchymal cells form human bone marrow capable of osteogenic differentiation Results: Identification of differentially regulated genes with aging in a highly enriched human bone marrow mesenchymal cell population. Conclusions: we have for the first time identified age-related differential gene expression and DNA methylation patterns in a highly enriched human bone marrow mesenchymal cell populationprofiles. Our results show that NGS offers a comprehensive and more accurate quantitative and qualitative evaluation of mRNA content within a cell or tissue. We conclude that RNA-seq based transcriptome characterization would expedite genetic network analyses and permit the dissection of complex biologic functions.

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