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Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [muscle]

ABSTRACT: Genome wide DNA methylation profiling of 4 human tissues of various ages: 51 vastus lateralis samples.The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode provided for batch normalization

ORGANISM(S): Homo sapiens

PROVIDER: GSE49908 | GEO | 2013/08/16

SECONDARY ACCESSION(S): PRJNA215305

REPOSITORIES: GEO

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Differential DNA methylation with age displays both common and dynamic features across human tissues that are influenced by CpG landscape [muscle]

Project description:Genome wide DNA methylation profiling of 4 human tissues of various ages: 51 vastus lateralis samples.The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Sentrix barcode provided for batch normalization 500ng of genomic DNA was bisulfite converted using EZ-96 DNA Methylation Kit from ZymoResearch, and hybridized to beadcheaps according to Illumina Infinium 27k Human DNA methylation standard procedures.

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