Adaptation of Propionibacterium freudenreichii to the colon environment

ABSTRACT: Mechanisms allowing P. freudenreichii adaptation to digestive stresses have been only studied in vitro so far. Our aim was therefore to study P. freudenreichii metabolic adaptation to intra-colonic conditions in situ. We maintained a pure culture of P. freudenreichii CIRM-BIA1, contained in a dialysis bag, within the colon of vigilant piglets during 24 hours. A transcriptomic analysis identified the metabolic pathways induced by this environment, in comparison with control propionibacteria maintained in spent culture medium.

ORGANISM(S): Propionibacterium freudenreichii

PROVIDER: GSE50089 | GEO | 2013/12/11

SECONDARY ACCESSION(S): PRJNA215993

REPOSITORIES: GEO