Tgif1 regulates quiescence and self-renewal signaling pathways of hematopoietic stem cells (HSCs)

ABSTRACT: In this study we demonstrate that Tgif1 has a role in HSCs maintenance, self-renewal and quiescence. RNA sequencing data of LSK cells (HSCs enriched cell population) from Tgif1-/- and wild type mice implicates that multiple pathways involved in HSC quiescence and self-renewal are disturbed in Tgif1 deficient mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE50739 | GEO | 2013/09/10

SECONDARY ACCESSION(S): PRJNA218619

REPOSITORIES: GEO