Highly efficient methane biocatalysis revealed in a methanotrophic bacterium

ABSTRACT: RNA-Seq profiling of Methylomicrobium alcaliphilum strain 20Z grown in batch on methane. The RNA-Seq work is one part of a systems approach to characterizing metabolism of 20Z during growth on methane. We demonstrate that methane assimilation is coupled with a highly efficient pyrophosphate-mediated glycolytic pathway, which under O2 limitation participates in a novel form of fermentation-based methanotrophy. This surprising discovery suggests a novel mode of methane utilization in oxygen-limited environments, and opens new opportunities for a modular approach towards producing a variety of excreted chemical products using methane as a feedstock.

ORGANISM(S): Methylotuvimicrobium alcaliphilum 20Z

PROVIDER: GSE51145 | GEO | 2013/09/25

SECONDARY ACCESSION(S): PRJNA221338

REPOSITORIES: GEO