Transcriptomics

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Expression data from mouse perigonadal white adipose tissue - various mutant conditions [gene-level analysis]


ABSTRACT: Progerin-expressing mice (HGPS-like) demonstrated increased energy metabolism and lipodystrophy. Increased mitochondrial biogenesis was found in adipose tissue from HGPS-like mice, whereas lamin C-only mice had fewer mitochondria. Thus we analyse which molecular pathways mediated the changes in adipose tissue caused by lamin C and progerin expression and the roles of these pathways in energy metabolism and aging.

ORGANISM(S): Mus musculus

PROVIDER: GSE51202 | GEO | 2015/06/05

SECONDARY ACCESSION(S): PRJNA221586

REPOSITORIES: GEO

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