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Genome-wide profiling of DNA methylation and expression identifies CIMP in myelodysplastic syndrome [Illumina]

ABSTRACT: To identify genes hypermethylated and transcriptionally downregulated, we have employed the Illumina Infinium HumanMethylation450 BeadChip and Agilent SurePrint G3 Human Gene Expression 8x60K. And we validated selected genes in cases and controls. eventually we estalished CIMP of MDS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE51758 | GEO | 2013/10/29

SECONDARY ACCESSION(S): PRJNA224961

REPOSITORIES: GEO

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Genome-wide profiling of DNA methylation and expression identifies CIMP in myelodysplastic syndrome [Illumina]

Project description:To identify genes hypermethylated and transcriptionally downregulated, we have employed the Illumina Infinium HumanMethylation450 BeadChip and Agilent SurePrint G3 Human Gene Expression 8x60K. And we validated selected genes in cases and controls. eventually we estalished CIMP of MDS. Bisulphite converted DNA from the 4 patients and 4 controls were hybridised to the Illumina Infinium 450k Human Methylation Beadchip

2013-10-29 | E-GEOD-51758 | biostudies-arrayexpress

Genome-wide profiling of DNA methylation and expression identifies CIMP in myelodysplastic syndrome [Agilent]

2013-10-29 | GSE51757 | GEO

Genome-wide profiling of DNA methylation and expression identifies CIMP in myelodysplastic syndrome [Agilent]

Project description:To identify genes hypermethylated and transcriptionally downregulated, we have employed the Illumina Infinium HumanMethylation450 BeadChip and Agilent SurePrint G3 Human Gene Expression 8x60K.And we validated selected genes in cases and controls. eventually we estalished CIMP of MDS. The gene expressions of four cases and four controls were measured.

2013-10-29 | E-GEOD-51757 | biostudies-arrayexpress

Gene expression analysis of stimulated primary ASM cells [mRNA]

Project description:mRNA expression was determined using the Agilent-G4851A SurePrint G3 Human GE 8x60K Microarray

2014-05-28 | GSE57764 | GEO

Expression data comparing BEL7402 HCC cells with or without PRMT6 stably repressed.

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Expression Profiles of SUM149 cell treated by ACY1215

Project description:Expression Profiles of SUM149 cell treated by ACY1215 at 0h, 3h, 6h and 12h by Agilent SurePrint G3 Human GE v3 8x60K.

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HMGB1 and Alu-siRNA inhibit the growth of human lung tumor cells

Project description:We performed expression profiling using microarray technology. The expression profiling identified genes or mechanism potentially regulating the proliferation of human lung cancer cells by BoxA of HMGB1 and Alu-siRNA transfection. The RNAs of our experiment were hybridized with Agilent SurePrint G3 Human GE 8X60K, V3 Microarrays (Agilent®).

2021-03-26 | GSE112429 | GEO

The impact of Pax5 overexpression on gene expression profile in A549 cells

Project description:Pax5, a transcription factor, is expressed exclusively in pro B cells. To understand the genes regulated by Pax5 in epithelial cells, we overexpressed Pax5 in lung cancer cell line A549 and examined the change of transcription profile using Agilent SurePrint G3 Human Gene Expression 8x60K v2 Microarray (Agilent Technologies).

2019-03-20 | GSE128539 | GEO

Genome-wide analysis of long noncoding RNA (lncRNA) expression for SAEC after treatment with demethylatiog agent (5-aza-dC) and histone deacetylase inhibitor (TSA)

Project description:To assess transcriptional regulation by DNA demethylation in SAEC, we carried out a microarray analysis of SAEC treated with a demethylating agent (5-aza-dC) and a HDAC inhibitor (TSA). We used the Agilent SurePrint G3 Human Gene Expression 8x60K v3 microarray which contains probes for 26,083 Entrez genes and 30,606 lncRNAs.

2017-06-28 | GSE82214 | GEO

Effect of a DP1 agonist BW245C on concanavalin A-induced hepatitis

Project description:To elucidate the effect of a prostaglandin D2 receptor DP1 agonist BW245C on concanavalin A (ConA) hepatitis, we performed DNA microarray using SurePrint G3 Mouse GE 8x60K Microarray. Mice were treated with ConA for 3 or 24 hr with vehicle or BW245C . Livers were collected, homogenized, and subjected to total RNA extraction.

2015-06-01 | GSE45413 | GEO

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