Expression data from rat androgenetic embryonic stem cells

ABSTRACT: The rat androgenetic embryonic stem cells (RahES cells) have only 21 chromosomes. However, they express pluripotency markers, differentiate into three germ layer cells as well as contribute to the germline as the normal diploid rat ES cells. Moreover, the RahES cells can produce fertile rats after intracytoplasmic injection into oocytes, thus are capable to transmit genetic modifications to offspring. We used microarrays to detail the global gene expression profile of RahES cells and identified distinct classes of up-regulated and down-regulated genes compared with the expression of normal diploid rat ES cells.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE51806 | GEO | 2013/12/15

SECONDARY ACCESSION(S): PRJNA225469

REPOSITORIES: GEO