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Expression profiling in Human Umbilical Vein Endothelial Cells (HUVEC)

ABSTRACT: Whole transcriptome gene expression profiling of Normal -(HUVEC) Human Umbilical Vein Endothelial Cells The HUVEC gene expression results analyzed in this study are further described in Kustermann S. et al. (2014) A real-time impedance based screening assay for drug induced vascular leakage.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52044 | GEO | 2014/01/07

SECONDARY ACCESSION(S): PRJNA226584

REPOSITORIES: GEO

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Expression profiling in Human Umbilical Vein Endothelial Cells (HUVEC)

Project description:Whole transcriptome gene expression profiling of Normal -(HUVEC) Human Umbilical Vein Endothelial Cells The HUVEC gene expression results analyzed in this study are further described in Kustermann S. et al. (2014) A real-time impedance based screening assay for drug induced vascular leakage. A NimbleGen Homo sapiens Expression Array [100718_HG18_opt_expr] study using total RNA recovered from HUVECs grown until 80% confluency. Each microarray measures the expression level of 23,611 genes using 45,033 probe sets with three 60-mer probes (PM) per probe set. Each probe set is represented once on the array.

2014-01-07 | E-GEOD-52044 | biostudies-arrayexpress

HUVEC Gene Expression of Irradiated Human Umbilical Vein Endothelial Cells

Project description:HUVEC Gene Expression of Irradiated Human Umbilical Vein Endothelial Cells

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Sex-specific transcriptional differences between non-treated male and female human umbilical vein endothelial cells (HUVEC)

Project description:Significant sex differences exist in cardiovascular diseases. It is largely unknown whether sexually dimorphic gene expression plays a role, and whether cells themselves show intrinsic sex differences. We therefore performed whole genome expression analyses in human umbilical vein endothelial cells (HUVEC) from five sample pools with equal amounts of four individual RNAs from either male or female donors (altogether 20 male and 20 female donors) and compared levels of gene transcription between the sexes. Genes indicative for greater immune responsiveness were stronger expressed in female compared to male HUVEC. There was a significant enrichment of 77 immune-related genes in female HUVEC.

2014-12-31 | GSE52212 | GEO

long read RNA-seq from endothelial cell of umbilical vein (ENCSR687RWI)

Project description:ENC4_505, ENC4_506 HUVEC rep1 primary human umbilical vein endothelial cell For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2022-12-04 | GSE219635 | GEO

Effects of blackcurrant extract on gene expression on Human Umbilical Vein Endothelial Cells.

Project description:To investigate new health functions by blackcurrant extract (BCE), we compare altered of the genes expression before and after BCE (2.0μg/ml) treatment in Human Umbilical Vein Endothelial Cells (HUVEC).

2018-10-25 | GSE121730 | GEO

Transcriptome Kinetics of 1[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl] imidazole (CDDO-Im) in Human Umbilical Vein Endothelial Cells (HUVEC): Mechanism of Action of Cytoprotection

Project description:This study evaluated temporal gene expression profiles to better characterize the early transcriptional events and their relationship to the dynamics of the cytoprotective response in human umbilical vein endothelial cells (HUVEC) to CDDO-.

2015-08-01 | GSE71622 | GEO

Real-time quantitative PCR analysis of Human Umbilical Vein Endothelial Cells (HUVEC)

Project description:In order to identify new markers of vascular cell senescence with potential in vivo implications, primary cultured Human Umbilical Vein Endothelial Cells (HUVECs), were analysed for microRNA (miR) expression.

2012-05-16 | GSE37972 | GEO

Gene expression analysis during morphogenesis of Human umbilical vein endothelial cells

Project description:Gene expression profiles during the differentiation of HUVEC on matrigel were analyzed. RNA was isolated from Human umbilical vein endothelial cell during morphogenesis. HG-U133 plus 2.0 microarray (54675 human genes; Affymetrix Santa Clara, CA, USA) was performed.

2011-02-09 | E-GEOD-27160 | biostudies-arrayexpress

Transcription profiling of human umbilical vein endothelial cells (HUVEC) treated with VEGF-A

Project description:Angiogenesis, the formation of new capillaries by sprouting from preexisting vessels, is mainly induced by VEGF-A. To identify genes which are induced by VEGF-A in endothelial cells, HUVEC were starved and induced by VEGF-A165 for 30, 60 and 150min. RNA of induced and uninduced cells was isolated and subjected to microarray analysis using Affymetrix microarray. Experiment Overall Design: Human umbilical vein endothelial cells were grown in complete EGM-2 medium in dense culture for four days without change of medium and before the stimulation in EGM-2 medium without growth factors over night. The cells were stimulated with 100ng/ml VEGF-A165 for 30, 60 and 150 min. RNA was isolated with Trizol according to the manufacturer's instructions.

2009-10-20 | E-GEOD-15464 | biostudies-arrayexpress

HUVEC Gene Expression of Irradiated Human Umbilical Vein Endothelial Cells

Project description:Ionizing radiation has become common for diagnostic and therapeutic purpose. Since it affects the cells at genetic level, it becomes necessary to evaluate its affects especially on endothelial cells which comprises the blood vessels and thus contributes in migration of blood cells, nutrients, oxygen etc. Human Umbilical Vein Endothelial Cells (HUVECs) are major model system used in vitro to study the nature and behaviour of endothelial cells.

2020-09-30 | GSE108723 | GEO

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