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Gene expression profiling in sinonasal sarcoma

ABSTRACT: Analyses of gene expression profiling in sinonasal sarcoma (SNS) harboring PAX3-MAML3 fusion gene or PAX3 rearrangement and other types of tumors without having such fusion or rearrangement. The results provide important information for further investigations of the PAX3-MAML3 fusion functions in SNS.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52252 | GEO | 2014/04/17

SECONDARY ACCESSION(S): PRJNA227901

REPOSITORIES: GEO

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Gene expression profiling in sinonasal sarcoma

Project description:Analyses of gene expression profiling in sinonasal sarcoma (SNS) harboring PAX3-MAML3 fusion gene or PAX3 rearrangement and other types of tumors without having such fusion or rearrangement. The results provide important information for further investigations of the PAX3-MAML3 fusion functions in SNS. Total RNA was obtained from FFPE tissues of 41 tumors including 8 SNS (6 with PAX3-MAML3 fusion and 2 with PAX3 rearrangement only) and 33 cases from other 10 different types of tumors. Gene expression profiling of fusion group including 8 SNA vs.non-fusion group including 33 control tumors were analyszed.

2014-04-17 | E-GEOD-52252 | biostudies-arrayexpress

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Project description:Novel PAX3-MAML3 Fusion in Biphenotypic Sinonasal Sarcoma

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Large scale screening for fusion genes in sarcoma patient samples

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