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An In Vivo Screen Uncovers Repression of Lipoprotein Lipase by MiR-29a as a Mechanism for Lipid Flux Away From the Liver

ABSTRACT: We screened for miRNA-regulated genes in adult mouse hepatocytes by a novel AAV8-Ttr-Cre delivery system deleting a floxed Dicer1 and blocking the processing of mature miRNAs. We then used a microarray to analyze the genes at T0 (just before injection), T1 (2 weeks after injection), T2 (4 weeks after injection)

ORGANISM(S): Mus musculus

PROVIDER: GSE52526 | GEO | 2015/01/01

SECONDARY ACCESSION(S): PRJNA229156

REPOSITORIES: GEO

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