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An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 1]

ABSTRACT: This dataset contains peptide array information from 120 patients from 5 different cancer types using classic blinded test/train method. This array is library 1 (GPL17600).

ORGANISM(S): synthetic construct Homo sapiens

PROVIDER: GSE52580 | GEO | 2013/12/15

SECONDARY ACCESSION(S): PRJNA229412

REPOSITORIES: GEO

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An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 1]

Project description:This dataset contains peptide array information from 120 patients from 5 different cancer types using classic blinded test/train method. This array is library 1 (GPL17600). A 1:500 dilution of human serum is added to a peptide array (GPL17600). This array is a two-up design, with 10420 peptides printed on the top and bottom of a standard glass microscope slide. Samples were run in duplicate. The average of the duplicates are listed here. 20 train and 20 blinded test samples were run.

2013-12-15 | E-GEOD-52580 | biostudies-arrayexpress

An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 2]

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An Immunosignature system for diagnosis of cancer [Cancer immunosignaturing - test 2]

Project description:This dataset contains peptide array information from 1516 patients from 12 different cancer types, 2 infectious diseases, and healthy controls using leave one out cross validation. This array is library 2 (GPL14921). A 1:500 dilution of human serum is added to a peptide array (GPL14921). This array is a one-up design, with 10286 peptides printed in duplicate on a standard glass microscope slide. 1516 patients samples from 14 different diseases and 1 control cohort were analyzed

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An Immunosignature system for diagnosis of cancer

Project description:This SuperSeries is composed of the SubSeries listed below.

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Project description:Gene expression test data set from rat liver samples exposed to either 150, 1500 or 2000 mg/kg of APAP for 3, 6 or 24 hours. The Supplementary file (appended below) contains the mapping for the decoding of blinded samples. Keywords: Dose response, Time course, Microarray, Gene expression

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Project description:Mycobacterium tuberculosis (Mtb) antigen-specific cellular response is promising for detectionof Mtb infection, but not efficient for diagnosis of TB. We firstly identified 16 TB disease-specific protein markers measured in the culture supernatant of Mtb-stimulated whole blood using a 640 human proteins array, the highest throughput antibody-based protein array available at the time when we did this study. Potential TB-related proteins were then analyzed across three different patient cohorts comprised of healthy controls, LTBI, non-TB pneumonia, and TB patients to evaluate how the biomarkers performed in diagnosing TB in the real clinical setting. The data finally reveal an eight-protein biosignature of TB.

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