Genomics

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Human Dental Pulp Cells Mature vs. Immature stages


ABSTRACT: We report screening of genes differentially expressed in cells isolated from immature and mature third molar teeth. Among them, a homeobox transcription factor, distal-less homeobox 4 (DLX4) was highly expressed in immature human dental pulp cells, and significantly enhanced iPSC colony formation in combination with OCT3/4, SOX2, and KLF4 to the level comparable with that using classical combination of Yamanaka's factors, OCT3/4, SOX2, KLF4, and c-MYC.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52853 | GEO | 2014/12/25

SECONDARY ACCESSION(S): PRJNA230361

REPOSITORIES: GEO

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