Transcriptome analysis of primary monocytes from HIV+ patients with differential responses to therapy

ABSTRACT: This study aimed at investigating the monocytic transcriptome distinction between patients with sustained virus suppression (BDL) and patients with virological failure during highly active antiretroviral therapy (HAART). This study provides the first transcriptomic distinctions in monocytes between viremic patients and BDLs on HAART. Our results reflected the outcome balanced between subversion of monocyte transcriptome by HIV and compensatory effect adapted by host cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE52900 | GEO | 2013/12/30

SECONDARY ACCESSION(S): PRJNA230417

REPOSITORIES: GEO