Expression profile of E. coli in response to exogenous addition of isopentenol

ABSTRACT: Exogenous isopentenol was added to a culture of E. coli and the RNA expression response was measured using Nimblegen arrays. Genes highly upregulated were then subsequently overexpressed to improve the tolerance to isopentenol toxicity. In addition a subset of genes that improved the tolerance were also overexpressed in a producing strain, leading to improved production over the empty vector control. This work is described in Foo et al, Improving microbial bio-gasoline production in E. coli using tolerance engineering (in preparation)

ORGANISM(S): Escherichia coli K-12 Escherichia coli

PROVIDER: GSE53138 | GEO | 2013/12/10

SECONDARY ACCESSION(S): PRJNA230972

REPOSITORIES: GEO