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Genome-wide analysis of gene expression within vitiligo lesional skin with active inflammation

ABSTRACT: Vitiligo skin samples with an active inflammatory infiltrate were selected for gene expression profiling in order to identify inflammatory pathways that drive depigmentation in vitiligo.

ORGANISM(S): Homo sapiens

PROVIDER: GSE53146 | GEO | 2013/12/12

SECONDARY ACCESSION(S): PRJNA231158

REPOSITORIES: GEO

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Genome-wide analysis of gene expression within vitiligo lesional skin with active inflammation

Project description:Vitiligo skin samples with an active inflammatory infiltrate were selected for gene expression profiling in order to identify inflammatory pathways that drive depigmentation in vitiligo. Total RNA was isolated from 10 deidentified human samples from formalin fixed, paraffin-embedded skin, 5 from vitiligo patients and 5 from controls. Control skin was age- and site-matched excision tips without pathology.

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Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

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