A novel Lysyl oxidase like 2 alternative splicing LOXL2 △e13 in esophageal squamous carcinoma cells

ABSTRACT: A novel alternative splicing isoform of LOXL2 △e13 was expressed ubiquitously in all cell lines and ESCC tissues. In contrast to the impaired deamination enzymatic activity compared with full length LOXL2, LOXL2 △e13 showed an enhanced ability to promote cell mobility and invasiveness in ESCC cells than full length LOXL2 through a different mechanism.

ORGANISM(S): Homo sapiens

PROVIDER: GSE53676 | GEO | 2016/01/01

SECONDARY ACCESSION(S): PRJNA232624

REPOSITORIES: GEO