Expression profiling of human adult postmortem brain tissue from Down syndrome and healthy control subjects

ABSTRACT: Down syndrome (DS) is the result of trisomy chromosome 21 but the mechanisms by which the genotype leads to the characteristic disease phenotype are unclear. We performed a microarray study using human adult brain tissue (dorsolateral prefrontal cortex) from DS subjects and healthy controls to characterise for the first time the human adult Down syndrome brain Keywords: disease state analysis

ORGANISM(S): Homo sapiens

PROVIDER: GSE5390 | GEO | 2007/07/27

SECONDARY ACCESSION(S): PRJNA96183

REPOSITORIES: GEO