Effect of NaCl concentration on the transcriptional network of E. coli in glucose minimal medium with glycine betaine

ABSTRACT: The growth rate of E. coli decrease continuously with NaCl concentration, however the pattern for metabolic efficiency as measured by optical density is corralated to a change in pattern in transcription data and proteomics.The analysis of the data suggest that between 4.5 and 5% NaCl, the metabolism switched from aerobic to fermentative pathways. The response to osmotic stress is similar to a response to oxidative stress. An example how a stagewise metabolic answer may be the result of continuously increasing stress.

ORGANISM(S): Escherichia coli K-12 Escherichia coli O157:H7 str. EDL933 Escherichia coli str. K-12 substr. MG1655 Escherichia coli CFT073 Escherichia coli O157:H7 str. Sakai

PROVIDER: GSE54512 | GEO | 2014/05/26

SECONDARY ACCESSION(S): PRJNA236751

REPOSITORIES: GEO