Alpha-amanitin treatment effect on intronic transcription

ABSTRACT: We compared the gene expression profiles of prostate carcinoma cells, LNCaP, treated or not with an inhibitor of RNA Polymerase II (RNAP II), alpha-amanitin. These experiments pointed to a fraction of intronic messages that seems to be insensitive to alpha-amanitin or up-regulated in cells with blocked RNAP II transcription. Keywords: RNA-polymerase II inhibition experiments

ORGANISM(S): Homo sapiens

PROVIDER: GSE5453 | GEO | 2007/03/29

SECONDARY ACCESSION(S): PRJNA95955

REPOSITORIES: GEO