Analysis of differentially-expressed genes in Tg(actb2:KIT-D816V) transgenic zebrafish versus wild-type adult kidneys

ABSTRACT: Transcriptional profiling of pooled adult kidneys from transgenic zebrafish expressing human KIT-D816V mutant gene versus wild-type zebrafish was performed. The aim of this experiment was to determine the expression and cellular changes caused by expression of KIT-D816V oncogene in the hematopoietic organ in zebrafish. This transgenic zebrafish represents a model of systemic mastocytosis with many features of this disease present in adults

ORGANISM(S): Danio rerio

PROVIDER: GSE54614 | GEO | 2014/02/03

SECONDARY ACCESSION(S): PRJNA237185

REPOSITORIES: GEO