Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Probing In vivo Brachyury Function with Tc mouse model

ABSTRACT: To identify Brachyury target genes in vivo and elucidate how Brachyury-mediated regulation contributes to early mouse developmental homeostasis and coordination, we performed mRNA-seq to compare gene expression profiles of WT and Tc/Tc embryos at both E7.5 ~ 8.0 and E10.0 ~ 10.5

ORGANISM(S): Mus musculus

PROVIDER: GSE54982 | GEO | 2014/03/10

SECONDARY ACCESSION(S): PRJNA238199

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Probing In vivo Brachyury Function with Tc mouse model

Project description:To identify Brachyury target genes in vivo and elucidate how Brachyury-mediated regulation contributes to early mouse developmental homeostasis and coordination, we performed mRNA-seq to compare gene expression profiles of WT and Tc/Tc embryos at both E7.5 ~ 8.0 and E10.0 ~ 10.5 WT and Tc/Tc embryos were isolated at both E7.5 ~ 8.0 and E10.0 ~ 10.5. Subsequently, directional mRNA-seq expriments were performed with wild-type and Tc/Tc whole embryos

2014-03-10 | E-GEOD-54982 | biostudies-arrayexpress

Probing Brachyury Function during ES cell differentiaiton

Project description:To probe how Brachyury regulates its target genes, we performed mRNA-seq to analyze gene expression changes after Brachyury depletion by the lentivirus-mediated shRNA

2014-03-10 | GSE54984 | GEO

Probing Brachyury Function during ES cell differentiaiton

Project description:To probe how Brachyury regulates its target genes, we performed mRNA-seq to analyze gene expression changes after Brachyury depletion by the lentivirus-mediated shRNA WT and Brachytury Knockdown embryoid bodies were collected at EB day 4. Subsequently, mRNA-seq expriments were performed with whole embryoid bodies

2014-03-10 | E-GEOD-54984 | biostudies-arrayexpress

Alicyclobacillus sp. TC strain:TC

Project description:Alicyclobacillus sp. TC strain:TC Genome sequencing and assembly

| PRJNA562382 | ENA

Escovopsis sp. TC strain:TC

Project description:Escovopsis sp. TC strain:TC Genome sequencing and assembly

| PRJNA388866 | ENA

Transcriptome of thyroid cancer (TC) cells after coculture with TC-induced macrophages

Project description:RNA sequencing data of TPC-1 cells (TC cell line) after co-culture with TC-induced macrophages. We used an in vitro co-culture model of a human TC cell line, TPC1 (RET/PTC rearrangement), and human primary monocytes.

2020-09-21 | GSE120391 | GEO

Genome wide chromatin changes in TC-32 and TC-71 Ewing sarcoma cell lines.

Project description:We performed ChIPseq on histone modification marks, transcriptional factors and chromatin architectural proteins in TC-32 and TC-71 Ewing sarcoma cell lines.

2019-08-07 | GSE115250 | GEO

Enterococcus sp. E843-TC isolate:E843-TC

Project description:Enterococcus sp. E843-TC isolate:E843-TC Genome sequencing

| PRJNA755459 | ENA

Map Brachyury-bound enhancers by ChIP-seq

Project description:To gain new mechanistic insights into highly-regulated lineage specification and morphogenetic processes during early embryogenesis, we applied ChIP-seq to identify transcriptional programs mediated by a key developmental regulator - Brachyury. Embryonic stem cells were differentiated into Brachyury-positive mesoendoderm cells. And, ChIP-seq experiments were carried out by two independent Brachyury antibodies.

2014-03-10 | E-GEOD-54978 | biostudies-arrayexpress

High-resolution Brachyury DNA-binding Sites Mapping by ChIP-exo

Project description:Mapping ultra high resolution of Brachyury:DNA interaction would provide us with valuable new mechanistic insights into complex molecular transactions at Brachyury-bound enhancers. Embryonic stem cells were differentiated into Brachyury-positive mesoendoderm cells. And, ChIP-exo experiment was then performed to identify detailed Brachyury-DNA binding profiles.

2014-03-10 | E-GEOD-54963 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data