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RA

ABSTRACT: patients affected by rheumatoid arthritis Keywords: repeat sample

ORGANISM(S): Homo sapiens

PROVIDER: GSE550 | GEO | 2003/11/30

SECONDARY ACCESSION(S): PRJNA85309

REPOSITORIES: GEO

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Project description:patients affected by rheumatoid arthritis

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Project description:Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease of unknown etiology and pronounced inter-patient heterogeneity. To characterize RA at the molecular level and to uncover key pathomechanisms, we performed whole-genome gene expression analyses. Synovial tissues from rheumatoid arthritis patients were compared to those from to normal donors. Keywords: repeat sample Rheumatoid in comparison to normal donors were investigated. For both groups samples derived from individual patients and or pools of patients were hybridised.

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Project description:mRNA expression levels in synovial fibroblasts in 6 rheumatoid arthritis patients versus 6 osteoarthritis patients. Keywords: disease type comparison, mRNA expression study

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2004-11-04 | E-GEOD-1919 | biostudies-arrayexpress

screen differential expressed microRNAs of RA patients

Project description:We screened the differential expressed microRNA from the rheumatoid arthritis patients and healthy person in their hydrops articuli CD4+ T cells. We screened the differential expressed microRNA from the rheumatoid arthritis patients and healthy person in their hydrops articuli CD4+ T cells. 1.Isolated the CD4+ T cells from the hydrops articuli cells of 2 rheumatoid arthritis patients. 2.Isolated the CD4+ T cells from healthy person's peripheral blood as control. 3.Isolation of total RNA from CD4+ T cells then sent the samples to KangChen Bio-tech Inc (Shanghai, China) where they were labeled, hybridized, scaned, normalied and transformed to the final data.

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screen differential expressed microRNAs of RA patients

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Project description:We study a new pathogenic, glycolytic PD1+ B cell population in sites of inflammation of patients with Rheumatoid Arthritis (RA).

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Project description:A genome-scale assessment of peripheral blood B-cell molecular homeostasis in patients with rheumatoid arthritis. Keywords: Rheumatoid Arthritis, B-cells

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