Project description:An 8 hours timecourse was performed with human DCs infected either with A/California/7/2009 and A/Brevig Mission/1/1918 (pandemic) or A/New Caledonia/20/99 and A/Texas/36/91 seosonal. Human monocyte derived dendritic cells (DCs) were infected either with chicken egg grown A/California/7/2009, A/Brevig Mission/1/1918, A/New Caledonia/20/99or A/Texas/36/91. Samples were taken and fixed in RNA stabilizing regaent at 2, 2.7, 3.3, 4, 5, 6, 7 and 8 hours. Cells exposed to chicken egg alantoic fluid served as a control. Infections with A/California/7/2009, A/New Caledonia/20/99 or A/Texas/36/91 were carried out at a BSL2 enviroment. Infections with A/Brevig Mission/1/1918 were carried out in a BSL3 enviroment in parralel to the BSL2 infections with cells from the same donor and cell preparation.

2015-08-20 | E-GEOD-55277 | biostudies-arrayexpress

Temporal Response to seasonal and pandemic H1N1 infection in human DCs- Donor 1

2015-08-20 | E-GEOD-55276 | biostudies-arrayexpress

Comparative transcriptomic analysis of acute host responses during 2009 pandemic H1N1 influenza infection in mouse, macaque, and swine

Project description:This SuperSeries is composed of the SubSeries listed below.

2012-08-14 | GSE40092 | GEO

Immune and transcriptomic response to seasonal influenza vaccination (TIV) in mice

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2016-06-01 | E-GEOD-68771 | biostudies-arrayexpress