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Transcriptional response in influenza-infected lungs from C57BL/6 wt, 129S7 wt and IFNAR-/- (129) mice

ABSTRACT: We used microarrays to analyse the global program of gene expression in response to Influenza A (X31) infection in lungs from C57BL/6 wt, 129S7 wt and IFNAR-/- (129) mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE55403 | GEO | 2014/04/30

SECONDARY ACCESSION(S): PRJNA239518

REPOSITORIES: GEO

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Transcriptional response in influenza-infected lungs from C57BL/6 wt, 129S7 wt and IFNAR-/- (129) mice

Project description:We used microarrays to analyse the global program of gene expression in response to Influenza A (X31) infection in lungs from C57BL/6 wt, 129S7 wt and IFNAR-/- (129) mice. Mock- or 5 day influenza A (X31)-infected total lungs from mice with the indicated genotypes were collected and processed for expression profiling.

2014-04-30 | E-GEOD-55403 | biostudies-arrayexpress

OVX/P4/UTX 129/SvImJ WT

Project description:OVX/P4/UTX 129/SvImJ WT

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Transcriptional respose at 18hrs in Interferon treated lungs from C57BL/6 wt mice

Project description:We used microarrays to analyse the global programme of gene expression in response to intranasal interferon treatment (IFNa4 and IFNl2) in lungs from C57BL/6 wt mice

2016-11-22 | GSE70628 | GEO

Analysis of transcriptional differences between ZIKV-infected Ifnar-/- and Ifnar+/- placentas

Project description:Purpose: While type I interferons (IFN) are important for control of viral replication, we see that, upon infection of Ifnar-/- females were crossed to Ifnar+/- males with ZIKV, only Ifnar+/- fetuses are resorbed or develop severe growth restriction. To identify how IFN may be altering placenta development, we performed RNAsequencing on infected and uninfected Ifnar-/- and Ifnar+/- placentas. Methods: Ifnar-/- females were crossed to Ifnar+/- males and infected intravaginally with Cambodian ZIKV at E5.5. Placentas were harvested from infected and uninfected pregnant dams at E10.5. Results/ Conclusions: Comparison of ZIKV-infected Ifnar-/- and Ifnar+/- shows an elevated interferon stimulated gene (ISG) signature in Ifnar+/- placentas but does not reveal any underlying developmental defects that may be causing defects in placenta development.

2017-12-31 | GSE98423 | GEO

Transcriptome analysis of WT and ATRX KO Cast x 129 mouse ES cells

Project description:Analysis of gene expression in WT and ATRX KO Cast x 129 Mouse ES cells

2015-04-16 | GSE59269 | GEO

OVX/P4&oil/UTX 129 WT vs. Hoxa-10-/-

Project description:OVX/P4&oil/UTX 129 WT vs. Hoxa-10-/-

| PRJNA99527 | ENA

Transcriptome analysis of WT and ATRX KO Cast x 129 mouse ES cells

Project description:Analysis of gene expression in WT and ATRX KO Cast x 129 Mouse ES cells Paired end RNA-seq analysis of PolyA selected RNA and PolyA depeleted RNA from in both wildtype nd ATRX knocked out Castx129 Mouse ES Cells

2015-04-16 | E-GEOD-59269 | biostudies-arrayexpress

OVX/P4/UTX 129/SvImJ WT B

Project description:Female mice used were 129/SvImJ wildtype (Jackson Lab), 10-16 weeks of age. 14 days after ovariectomy, mice were injected subcutaneously with progesterone dissolved in sesame oil (Sigma; 0.2mg/0.1mL/mouse), followed by sacrifice and removal of uterine horns at various times after injection. 8 uterine horns from 4 mice were pooled to form one sample. Total RNA preparation, cRNA labeling and hybridization were performed according to recommendations by Affymetrix. Keywords: time-course

2002-12-10 | GSE107 | GEO

OVX/P4/UTX 129/SvImJ WT A

2002-12-10 | GSE106 | GEO

Single-cell RNAseq of mouse brain infected with Langat virus in WT and Ifnar KO

Project description:In this project we studied the effect of Langat infection (LGTV strain TP21) on the brains of mice, both wild-type and Ifnar-/-. Nuclei of the brain were isolated and subjected to 10x 3' scRNAseq.

2023-03-19 | E-MTAB-12131 | biostudies-arrayexpress

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