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Genome-wide analysis of gene expression in MDA-MB-231 breast cancer cells in response to conditional miRNA mediated BSP knockdown.

ABSTRACT: Our goal was to identify the genes, which are modulated following conditional BSP knockdown for 3 and 6 days. Thus, to elucidate the BSP relevance and to broaden the knowledge on the affected signalling pathways.

ORGANISM(S): Homo sapiens

PROVIDER: GSE55432 | GEO | 2014/02/28

SECONDARY ACCESSION(S): PRJNA239570

REPOSITORIES: GEO

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Genome-wide analysis of gene expression in MDA-MB-231 breast cancer cells in response to conditional miRNA mediated BSP knockdown.

Project description:Our goal was to identify the genes, which are modulated following conditional BSP knockdown for 3 and 6 days. Thus, to elucidate the BSP relevance and to broaden the knowledge on the affected signalling pathways. Cell pellets were collected after 3 and 6 days of cultivating the cells in media with or without doxycycline. There were duplicated total RNA samples for each time interval and each condition.The mRNA expression of the in vitro miRNA treated cells was compared to the respective +dox control.

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