Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

EcadEGFP expression in MDA-MB-134 and IPH-926

ABSTRACT: This experiment aims to study transcriptional alterations induced by reconstitution of wild type E-cadherin expression in human lobular breast cancer cells harbouring deleterious, somatic CDH-1 mutations

ORGANISM(S): Homo sapiens

PROVIDER: GSE55529 | GEO | 2014/03/04

SECONDARY ACCESSION(S): PRJNA239879

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

EcadEGFP expression in MDA-MB-134 and IPH-926

Project description:This experiment aims to study transcriptional alterations induced by reconstitution of wild type E-cadherin expression in human lobular breast cancer cells harbouring deleterious, somatic CDH-1 mutations Two cell lines (IPH-926 and MDA-MB-134) expressing synthetic Ecad (EcadEGFP) or not (EGFP) were compared against each other. Analysis were conducted in triplicates (IPH-926) and quadruplicates (MDA-MB-134), respectively.

2014-03-04 | E-GEOD-55529 | biostudies-arrayexpress

EcadEGFP expression in MDA-MB-134 and IPH-926

Project description: Not available

| S-ECPF-GEOD-55529 | biostudies-other

ChIP-seq of MDA-MB-134 cell line

2014-01-15 | GSE51022 | GEO

ChIP-seq of MDA-MB-134 cell line

Project description:We performed ChIP seq experiment in MDA-MB-134 cell line in order to map the estrogen receptor alpha (ER) binding sites following the estrogen treatment in an ILC model. We have characterized the genome wide recruit of ER and scaned the binding sites for the presence of cofactor motifs. The binding peaks were also correlated to E2 regulated genes in this ILC model. Four samples were subjected to high throughput sequencing: E-ER (estrogen treated followed by ER IP), E-IgG (estrogen treated followed by IgG), V-ER (EtOH treated followed by ER IP) and Input (MCF7 genomic DNA)

2014-01-15 | E-GEOD-51022 | biostudies-arrayexpress

Cadherin-11 depletion in aggressive MDA-MB-231 breast cancer cells.

Project description:Cadherin-11 expression is associated with tumor progression and metastasis in various cancers, including basal-like breast carcinoma and advanced prostate cancer, and invasive cell lines, yet is absent in normal epithelium. We now show cadherin-11 attenuation in aggressive breast and prostate cancer cells results in marked decreases in proliferation, migration, and invasion. Cadherin-11 depletion in MDA-231 cells prevents tumor growth in mice and alters gene expression associated with poor prognosis malignancies. Additionally, a novel small molecule inhibitor targeting its unique adhesive interface significantly inhibits the growth and migration of cadherin-11 positive cells. Cadherin-11 is essential for malignant progression of MDA-231 basal-type cells, and may serve as both an aggressive tumor marker and viable therapeutic target for poor prognosis carcinomas expressing it.

2010-02-22 | GSE14943 | GEO

IPH-926 human lobular breast cancer cells

2011-12-21 | GSE28089 | GEO

IPH-926 human lobular breast cancer cells

Project description:IPH-926 is an anticancer drug-resistant tumor cell line derived from a chemo-refractory human infiltrating lobular breast cancer (ILBC). IPH-926 ILBC cells were subjected to gene expression profiling using an Affymetrix HG U133 Plus 2.0 array. To characterize the global gene expression of IPH-926, cells were subjected to transcriptional profiling using the Affymetrix HG U133 Plus 2.0 technology. The correct identity of the IPH-926 cells subjected to gene expression profiling was authenticated by short tandem repeat (STR) profiling.

2011-12-21 | E-GEOD-28089 | biostudies-arrayexpress

ALDH1A3-mediated gene expression in MDA-MB-231 cells and MDA-MB-468 cells

Project description: Not available

| S-ECPF-GEOD-49322 | biostudies-other

Expression data from parental MDA-MB-231 cells and MDA-MB-231(SA) variant

Project description: Not available

| S-ECPF-GEOD-20085 | biostudies-other

Effects of FSTL1 on cell proliferation in breast cancer cell line MDA‑MB‑231 and its brain metastatic variant MDA‑MB‑231‑BR.

Project description: Not available

| S-EPMC5780039 | biostudies-literature