Transcriptomics,Genomics

Dataset Information

40

Glomerular transcriptomic analysis of the influence of Genetic background effect during anti-GBM glomerulonephritis in mice


ABSTRACT: We analyzed the impact of the genetic background during experimental passive non-accelerated anti-glomerular basement membrane glomerulonephritis (anti-GBM-GN) (an equivalent to nephrotoxic nephritis) in two different mouse genetic backgrounds (C57BL6/J vs 129S2svPAS/crl). Glomerular extracts have been made at an early time point (e.g day 4 of the induction of the glomerulonephritis). RNA have been extracted following standard procedures. Overall design: 3 mice per group have been compared. 3 Control mice from each background. And 3 anti-GBM-GN challenged mice from each Genetic background, corresponding to 12 samples in total.

INSTRUMENT(S): [Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

SUBMITTER: Laurent MESNARD  

PROVIDER: GSE56236 | GEO | 2014-07-14

SECONDARY ACCESSION(S): PRJNA242677

REPOSITORIES: GEO

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