Gene expression of CD14+ cells from RA, PsA and PsO patients with Infliximab treatment

ABSTRACT: objection: The immune inflammatory disorders rheumatoid arthritis (RA), psoriatic arthritis (PsA) and psoriasis (Ps) share common pathologic features and show responsiveness to anti-tumor necrosis factor (TNF) agents yet they are phenotypically distinct. The aim of this study was to examine if anti-TNF therapy is associated with divergent gene expression profiles in circulating cells and target tissues of patients with these diseases Method: Peripheral blood CD14+ and CD14- cells were isolated from 9 RA, 12 PsA and 10 Ps patients before and after infliximab (IFX) treatment

ORGANISM(S): Homo sapiens

PROVIDER: GSE57383 | GEO | 2014/10/29

SECONDARY ACCESSION(S): PRJNA246407

REPOSITORIES: GEO