Genomics

Dataset Information

0

Expression data from 1499 cells, a mouse ADM/PanIN1-derived pancreatic ductal cell line, and the mouse pancreatic ductal adenocarcinoma (PDAC) AH375 cell line.


ABSTRACT: In a Kras-driven mouse model of multistage pancreatic cancer progression, decreased p-ERK levels correlate with tumor initiation. In cells derived from this model, transformed cells with low p-ERK levels express markers of pluripotency and demonstrate phenotypes of tumor initiating cells, such as formation of free-floating tumor spheres. Here, a comparison of gene expression from the 1499 cell line, which are premalignant cells isolated from mouse ADM (acinar-to-ductal metaplasia) and PanIN1 (pancreatic intraepithelial lesions), and the AH375 cell line, established from mouse PDAC, was performed.

ORGANISM(S): Mus musculus

PROVIDER: GSE57566 | GEO | 2016/05/10

SECONDARY ACCESSION(S): PRJNA246713

REPOSITORIES: GEO

Similar Datasets

2022-06-01 | GSE179248 | GEO
2022-07-01 | GSE195560 | GEO
2022-07-25 | GSE208536 | GEO
2019-09-12 | GSE111540 | GEO
2021-01-07 | PXD018296 | Pride
2012-11-01 | E-GEOD-37480 | biostudies-arrayexpress
2015-09-30 | GSE40895 | GEO
2023-09-05 | GSE234045 | GEO
2014-12-30 | GSE63348 | GEO
2012-11-01 | GSE37480 | GEO