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MiR-133b regulates the expression of the actin protein TAGLN2 during oocyte growth and maturation: a potential target for infertility therapy

ABSTRACT: In this study, the expression of miRNAs in metaphase I (MI) oocytes treated with or without insulin-like growth factor 1 (IGF-1) was observed by microRNA microarray analysis. Results show that 145 miRNAs were up-regulated and 200 miRNAs were down-regulated in MI oocytes after IGF-1 treatment. MiR-133b, which was up-regulated more than 30-fold, was chosen for further research.

ORGANISM(S): Homo sapiens

PROVIDER: GSE57657 | GEO | 2014/12/31

SECONDARY ACCESSION(S): PRJNA247460

REPOSITORIES: GEO

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