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Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient iPSCs [RNA-seq]

ABSTRACT: We compared the epigenetic status of the mutant and disease-free iPSCs at the whole genome level. Whole epigenome profiling based on trimethylated H3K4 (H3K4me3) showed concordant epigenetic remodeling in the two corrected clones when compared with two mutant iPSC clones.

ORGANISM(S): Homo sapiens

PROVIDER: GSE57826 | GEO | 2014/05/21

SECONDARY ACCESSION(S): PRJNA248196

REPOSITORIES: GEO

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Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient iPSCs [ChIP-seq]

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