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Gene expression in diploid and evolved tetraploid RPE-1 and BJ-1 cells

ABSTRACT: Both diploid RPE-1 and BJ-1 cells were made tetraploid by transient treatment with the cytokinesis inhibitor DCD. Proliferating tetraploids from both BJ-1 and RPE-1 were selected and isolated. The gene expression profiles of the proliferating tetraploid cells were then compared to the diploids from which they originated.

ORGANISM(S): Homo sapiens

PROVIDER: GSE57864 | GEO | 2014/05/22

SECONDARY ACCESSION(S): PRJNA248291

REPOSITORIES: GEO

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Gene expression in diploid and evolved tetraploid RPE-1 and BJ-1 cells

Project description:Both diploid RPE-1 and BJ-1 cells were made tetraploid by transient treatment with the cytokinesis inhibitor DCD. Proliferating tetraploids from both BJ-1 and RPE-1 were selected and isolated. The gene expression profiles of the proliferating tetraploid cells were then compared to the diploids from which they originated. Triplicate biological samples were collected and analyed.

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