Single cell RNA-seq of primary human glioblastomas

ABSTRACT: We report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, MGH28, MGH31) cultured under serum free (GSC) and differentiated (DGC) conditions. This dataset highlights intratumoral heterogeneity with regards to the expression of de novo derived transcriptional modules and established subtype classifiers.

ORGANISM(S): Homo sapiens

PROVIDER: GSE57872 | GEO | 2014/06/12

SECONDARY ACCESSION(S): PRJNA248302

REPOSITORIES: GEO