Genomics

Dataset Information

33

Gene Expression Data in Human Monocyte-derived Dendritic Cell (MoDC) from Young and Aged Donors


ABSTRACT: Dendritic cells (DCs) are major antigen-presenting cells that play a key role in initiating and regulating innate and adaptive immune responses. DCs are critical mediators of tolerance and immunity. The functional properties of DCs changes with age. The purpose of this study was to define the age-associated molecular changes in DCs by gene array analysis using Affymatrix GeneChips. We identified up and down-regulated gene expression changes in DC from aged donors compared to young donors. Overall design: Total 9 MoDC RNA samples from four young donors (20-27 years) and five aged donors (77-84 years) were analyzed using Affymetrix HG-U133A_2 Gene Arrays to compare differential gene expression changes in MoDC between aged and young groups

INSTRUMENT(S): [HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array

ORGANISM(S): Homo sapiens  

SUBMITTER: Sudhir Gupta 

PROVIDER: GSE58015 | GEO |

SECONDARY ACCESSION(S): PRJNA248715

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
GSE58015_RAW.tar Raw
filelist.txt Txt
Items per page:
1 - 2 of 2

Similar Datasets

2014-05-28 | E-GEOD-58015 | ArrayExpress
2014-01-01 | S-EPMC4156347 | BioStudies
2016-01-01 | S-EPMC4715434 | BioStudies
2019-01-01 | S-EPMC6298184 | BioStudies
2014-01-01 | S-EPMC4165882 | BioStudies
2016-03-31 | E-GEOD-52480 | ArrayExpress
2017-04-19 | E-GEOD-75416 | ArrayExpress
2016-02-05 | E-GEOD-72264 | ArrayExpress
| GSE72264 | GEO
1000-01-01 | S-EPMC5442814 | BioStudies