Transcriptomics

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Gene expression of Bone marrow-derived macrophages isolated in ERR-alpha knock-out mice


ABSTRACT: We investigated the molecular mechanisms by which ERRα negatively regulates TLR-signaling pathways. To examine this, we performed global gene expression analysis of ERRα+/+ and ERRα-/- BMDMs after LPS stimulation. Microarray analysis revealed that several genes encoding various TLR-negative regulators were downregulated in LPS-stimulated ERRα-/- BMDMs, when compared with ERRα+/+ BMDMs

ORGANISM(S): Mus musculus

PROVIDER: GSE58515 | GEO | 2014/06/17

SECONDARY ACCESSION(S): PRJNA252810

REPOSITORIES: GEO

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