Genomics

Dataset Information

0

Global gene expression profiling reveals similarities and differences among mouse pluripotent stem cells


ABSTRACT: We present a compendium DNA microarray analysis of multiple mouse ESCs and EGCs from different genetic backgrounds (strains 129 and C57BL/6) cultured under standard conditions and in differentiation-promoting conditions by the withdrawal of Leukemia Inhibitory Factor (LIF) or treatment with retinoic acid (RA). All pluripotent cell lines showed similar gene expression patterns, which separated them clearly from other tissue stem cells with lower developmental potency. Differences between pluripotent lines derived from different sources (ESC vs. EGC) were smaller than differences between lines derived from different mouse strains (129 vs. C57BL/6). Keywords: cell type comparison design

ORGANISM(S): Mus musculus

PROVIDER: GSE5914 | GEO | 2007/05/11

SECONDARY ACCESSION(S): PRJNA97355

REPOSITORIES: GEO

Similar Datasets

| E-GEOD-5914 | biostudies-arrayexpress
| E-GEOD-43398 | biostudies-arrayexpress
2017-04-12 | GSE68733 | GEO
2017-05-18 | GSE94481 | GEO
2011-03-24 | GSE24220 | GEO
| E-GEOD-24220 | biostudies-arrayexpress
| E-GEOD-61472 | biostudies-arrayexpress
2008-10-01 | GSE11281 | GEO
| E-GEOD-14481 | biostudies-arrayexpress
| E-GEOD-11281 | biostudies-arrayexpress