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Human A375 melanoma cell line treated with trifluorothymidine (TFT) and lactimidomycin (LTM)

ABSTRACT: To generate drug signatures in human A375 melanoma cell lines. A375 cell line was plated at 4 x 105 cells/mL overnight and treated with trifluridine or lactimidomycin at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

ORGANISM(S): Homo sapiens

PROVIDER: GSE59183 | GEO | 2018/01/01

SECONDARY ACCESSION(S): PRJNA254572

REPOSITORIES: GEO

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Human WM35 melanoma cell line treated with trifluorothymidine(TFT) and lactimidomycin(LTM)

Project description:To generate drug signatures in human WM35 melanoma cell line. WM35 cell line was plated at 4 x 105 cells/mL overnight and treated with trifluridine or lactimidomycin at 75% inhibitory concentrations (IC75, determined previously at 72h of treatment) or DMSO (vehicle) for 8h or 24h before harvest.

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Gene expression profiling of isogenic malignant melanoma A375-BRAFV600E/NRASQ61 and A375-BRAFV600E/NRASQ61K cell lines

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