Genomics

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Acquired resistance to mutant-selective EGFR inhibitor AZD9291 is associated with increased dependence on RAS signaling


ABSTRACT: To compare gene copy number in cell populations with acquired resistance to specified EGFR inhibitors to parental cell lines. The aim of the experiment was to determine whether gain or loss of copy number of particular genes was associated with resistance to particular EGFR inhibitors.

ORGANISM(S): Homo sapiens

PROVIDER: GSE59239 | GEO | 2015/04/14

SECONDARY ACCESSION(S): PRJNA254803

REPOSITORIES: GEO

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