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Genome-wide expression of the leukemic cells with different sensitivity to AraC

ABSTRACT: To examine the molecular alterations in cells with different sensitivity, genome-wide expression of the leukemic cells was profiled, revealing that overall 366 and 212 genes became upregulated or downregulated, respectively, in the resistant cells. Many of these genes are involved in the regulation of cell cycle, cellular proliferation, and apoptosis.

ORGANISM(S): Mus musculus

PROVIDER: GSE59420 | GEO | 2015/07/10

SECONDARY ACCESSION(S): PRJNA255279

REPOSITORIES: GEO

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Genome-wide expression of the leukemic cells with different sensitivity to AraC

Project description:To examine the molecular alterations in cells with different sensitivity, genome-wide expression of the leukemic cells was profiled, revealing that overall 366 and 212 genes became upregulated or downregulated, respectively, in the resistant cells. Many of these genes are involved in the regulation of cell cycle, cellular proliferation, and apoptosis. gene expression of myeloid leukemic cell

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