Genomics

Dataset Information

35

Autoantibody Profiles in Collagen Disease Patients with Interstitial Lung Disease


ABSTRACT: Auto-antibody (Ab) profiles between acute-onset diffuse ILD (AoDILD) and stable states of 25 collagen disease patients were compared to screen biomarkers or pathogenic auto-Abs. Overall design: Auto-Ab levels in pooled sera were compared between the AoDILD and stable states with ProtoArray.

INSTRUMENT(S): Invitrogen ProtoArray v5.0 (full array layout)

SUBMITTER: Hiroshi Furukawa 

PROVIDER: GSE59687 | GEO | 2017-02-09

SECONDARY ACCESSION(S): PRJNA255953

REPOSITORIES: GEO

Dataset's files

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Publications

Autoantibody Profiles in Collagen Disease Patients with Interstitial Lung Disease (ILD): Antibodies to Major Histocompatibility Complex Class I-Related Chain A (MICA) as Markers of ILD.

Furukawa Hiroshi H   Oka Shomi S   Shimada Kota K   Masuo Kiyoe K   Nakajima Fumiaki F   Funano Shunichi S   Tanaka Yuki Y   Komiya Akiko A   Fukui Naoshi N   Sawasaki Tatsuya T   Tadokoro Kenji K   Nose Masato M   Tsuchiya Naoyuki N   Tohma Shigeto S  

Biomarker insights 20150816


Interstitial lung disease (ILD) is frequently associated with collagen disease. It is then designated as collagen vascular disease-associated ILD (CVD-ILD), and influences patients' prognosis. The prognosis of acute-onset diffuse ILD (AoDILD) occurring in patients with collagen disease is quite poor. Here, we report our investigation of auto-antibody (Ab) profiles to determine whether they may be useful in diagnosing CVD-ILD or AoDILD in collagen disease. Auto-Ab profiles were analyzed using the  ...[more]

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