Genomic targets sites of the Candida glabrata transcription factor Pdr1

ABSTRACT: Pdr1 is the major regulator of azole resistance in the fungal pathogen Candida glabrata. Earlier experiments demonstrated that expression of Pdr1 itself is increased when cells lose their mitochondrial genome (rho0). Here we use chromatin immunoprecipitation coupled with highthroughput sequencing (ChIP-seq) to map the genomic binding sites for Pdr1 in both normal and rho0 cells. These data provide the first look at genes that are likely to represent the direct targets of Pdr1 in this important pathogen.

ORGANISM(S): Nakaseomyces glabratus CBS 138

PROVIDER: GSE59839 | GEO | 2014/09/12

SECONDARY ACCESSION(S): PRJNA256336

REPOSITORIES: GEO