Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

PPARγ controls alveolar macrophage identity

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Mus musculus

PROVIDER: GSE60249 | GEO | 2014/09/28

SECONDARY ACCESSION(S): PRJNA257837

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

PPARÎ³ controls alveolar macrophage identity

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-09-28 | E-GEOD-60249 | biostudies-arrayexpress

PRC2 controls adult neuron identity and protects neurons against neurodegeneration

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2016-07-29 | E-GEOD-84245 | biostudies-arrayexpress

PPARγ controls alveolar macrophage identity [part2]

Project description:Tissue-resident macrophages comprise heterogeneous populations with unique functions and distinct gene expression signatures. While it has been established that they mostly originate from embryonic progenitors, the signals inducing a characteristic tissue-specific differentiation program remain unknown. Here we identify PPARγ as the crucial transcription factor determining perinatal alveolar macrophage (AM) development and identity. Development of the fetal monocyte derived AM precursor was largely abrogated in CD11c-Cre/Ppargfl/fl mice. To reveal the underlying changes in gene expression, we performed microarray analysis of sorted WT and KO AM and pre-AM from 3 different timepoints. Part2: adult sorts & array

2014-09-28 | GSE60248 | GEO

PPARγ controls alveolar macrophage identity [part1]

2014-09-28 | GSE60247 | GEO

Ligand-insensitive PPARγ controls progressive or reinforcing macrophage polarization as an epigenomic ratchet of transcriptional memory

Project description:This SuperSeries is composed of the SubSeries listed below.

2018-06-20 | GSE115505 | GEO

The sexual identity of adult intestinal stem cells controls organ size and plasticity.

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2016-02-18 | E-GEOD-74775 | biostudies-arrayexpress

Cytomegalovirus subverts macrophage identity

Project description:This SuperSeries is composed of the SubSeries listed below.

2021-06-15 | GSE159389 | GEO

Translational regulation of specific mRNAs controls feedback inhibition and survival during macrophage activation

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2014-06-19 | E-GEOD-52451 | biostudies-arrayexpress

Signal-responsive transcription factors cooperate to establish alveolar macrophage identity

Project description:This study includes RNA-Seq, ATAC-Seq, and HT-ChIP-mentation-Seq assay data performed on alveolar macrophages from wild-type and RXRαβ-deficient mice. Through this multifaceted analysis, we aimed to elucidate the transcriptional and epigenetic landscape orchestrated by RXRs in alveolar macrophages. This SuperSeries is composed of the SubSeries listed below.

2026-05-13 | GSE243165 | GEO

Genetic Variation Determines PPARγ Function and Antidiabetic Drug Response In Vivo

Project description:This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

2015-07-02 | E-GEOD-64460 | biostudies-arrayexpress