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DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII [MeDIP]

ABSTRACT: We measured the methylation levels of gene promoters of cerebral cortex of mice. We used MeDIP-array, immunoprecipitating genomic DNA with an antibody against methylated DNA and measuring methylation levels using custom arrays. The input DNA was used as control.

ORGANISM(S): Mus musculus

PROVIDER: GSE60656 | GEO | 2015/09/01

SECONDARY ACCESSION(S): PRJNA259206

REPOSITORIES: GEO

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DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII [MeDIP]

Project description:We measured the methylation levels of gene promoters of cerebral cortex of mice. We used MeDIP-array, immunoprecipitating genomic DNA with an antibody against methylated DNA and measuring methylation levels using custom arrays. The input DNA was used as control. triplicates of frontal cortex DNA pools of 3 mice

2015-09-01 | E-GEOD-60656 | biostudies-arrayexpress

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DNA methylation at transcription start sites blocks TBP binding and transcription onset by RNApolII

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