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Identification of LncRNA Expression Signatures for Triple-negative Breast Cancer

ABSTRACT: To identify biologically and clinically novel lncRNAs potentially involved in the progression of breast cancer, we profiled the expression of lncRNAs in two stage III triple-negativebreast cancer tissues and their paired adjacent noncancerous tissues by LncRNA Array 3.0 (ArrayStar). Expression of the mostly upregulated lncRNA (BCAR4) from this signature was quantified in the breast caner tissue microarray by RNA In situ Hybridization and bioinformatic analysis of Oncomine database, confirming its correlation with breast cancer metastasis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE60689 | GEO | 2014/12/01

SECONDARY ACCESSION(S): PRJNA259367

REPOSITORIES: GEO

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