Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Saccharomyces cerevisiae deletion collections chemogenomic screen with sr7575

ABSTRACT: Growth assay in the presence of a toxic chemical (sr7575) that uses the barcoded collections of yeast gene deletions (haploid, diploid, DamP) to identify deletion strains that are hypersensitive to the drug.

ORGANISM(S): Saccharomyces cerevisiae S288C Saccharomyces cerevisiae

PROVIDER: GSE60934 | GEO | 2015/12/09

SECONDARY ACCESSION(S): PRJNA259859

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Saccharomyces cerevisiae deletion collections chemogenomic screen with Triclosan, Methylparaben and Ethylzingerone

Project description:Growth assay in the presence of a toxic chemical that uses the barcoded collections of yeast gene deletions (haploid, diploid, DamP) to identify deletion strains that are hypersensitive to the drug.

2019-12-31 | GSE125353 | GEO

Saccharomyces cerevisiae deletion collections chemogenomic screen with sr7575

Project description:Growth assay in the presence of a toxic chemical (sr7575) that uses the barcoded collections of yeast gene deletions (haploid, diploid, DamP) to identify deletion strains that are hypersensitive to the drug. Two-condition experiment â growth of a pool of strains in the presence or absence of the drug. Two independent biological replicates for each collection (haploids - homozygous and diploids â heterozigous). Data for the article: Shriya Raj, Karthik Krishnan, David S Askew, Olivier Helynck, Peggy Suzanne, Aureslien Lesnard, Sylvain Rault, Ute Zeidler, Christophe d'Enfert, Jean-Paul LatgÃ©, HÃ©lÃ¨ne Munier-Lehmann and Cosmin Saveanu. Toxicity of a novel antifungal compound is modulated by ERAD components. Antimicrobial Agents and Chemotherapy.

2015-12-09 | E-GEOD-60934 | biostudies-arrayexpress

Saccharomyces cerevisiae deletion and DAmP collections chemogenomic screen with Selenomethionine

Project description:Growth assay in the presence of Selenomethionine that uses the barcoded collections of yeast gene modification (deletion or DamP) to identify strains that are hypersensitive to the presence of the aminoacid.

2017-03-17 | GSE84340 | GEO

Saccharomyces cerevisiae deletion collections chemogenomic screen with Triclosan, Methylparaben and Ethylzingerone

Project description:Saccharomyces cerevisiae deletion collections chemogenomic screen with Triclosan, Methylparaben and Ethylzingerone

| PRJNA515907 | ENA

Strain abundance assay of barcoded DAmP loss of function S. cerevisiae strains exposed to various compounds

Project description:The ability to perform complex bioassays in parallel enables experiments otherwise impossible due to throughput and cost constraints. By way of example, highly parallel chemical-genetic screens using pooled collections of thousands of defined Saccharomyces cerevisiae gene deletion strains are feasible because each strain is barcoded with unique DNA sequences. It is, however, time consuming and expensive to individually barcode individual strains. To provide a simple and general method of barcoding yeast collections, we built a set of donor strains, called Barcoders, with unique barcodes that can be systematically transferred to any S. cerevisiae collection. We applied this technology by generating a collection of barcoded DAmP (Decreased Abundance by mRNA Perturbation) loss-of-function strains comprising 87.1% of all essential yeast genes. This test collection validates both the Barcoders and the DAmP collection as useful tools for genome-wide chemical genetic assays.

2008-07-03 | E-MEXP-1671 | biostudies-arrayexpress

Saccharomyces cerevisiae

Project description:Saccharomyces cerevisiae deletion and DAmP collections chemogenomic screen with Selenomethionine

| PRJNA328936 | ENA

Ploidy influences the cellular responses of gross chromosomal rearrangements in Saccharomyces cerevisiae

Project description:We investigated the effects of the ploidy on cellular response in strains carrying various types of gross chromosomal rearrangements. Fourteen mutated strains (6 haploid strains and 8 diploid strains) were compared to their associated parental strain (haploid or diploid parental strain). For each comparison, 2 microarray experiments implying biological replicates were performed.

2011-06-17 | E-GEOD-28285 | biostudies-arrayexpress

Mithramycin A chemogenomic profile

Project description:Mithramycin A in known to bind DNA but its exact cellular mechanism of action is still unclear. We used Affymatrix GenFlex_Tag_16K_V2 microarrays to profile sensitivity of genetically barcoded S. cerevisiae gene deletion strains to mithramycin A

2020-11-05 | GSE122458 | GEO

Saccharomyces cerevisiae

Project description:Responses to ethanol in haploid and diploid strain

| PRJNA124237 | ENA

Responses to ethanol in haploid and diploid strain

Project description:Diploid and haploid strains often exhibit different tolerance to variety of stresses. Transcriptome of acclimation to ethanol stress in diploid and haploid strain of Saccharomyces cerevisiae was analyzed. We analyzed transcriptome profiles of diploid and haploid strains in the presence of ethanol.

2010-01-30 | GSE20108 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data