Loss of p21 expression enhances DNA damage, cholestasis and hepatocarcinogenesis in the liver

ABSTRACT: Overexpression of p21 in NEMOΔhepa animals protects against DNA damage, acceleration of hepatocarcinogenesis and cholestasis. As strengthened by our LPS stimulation experiments, we identified a novel protective role of p21 against DNA damage.

ORGANISM(S): Mus musculus

PROVIDER: GSE61100 | GEO | 2015/03/01

SECONDARY ACCESSION(S): PRJNA260220

REPOSITORIES: GEO