Genomics

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DNA Methylation Patterns in Rat Mammary Carcinomas Induced by Pre- and Post-Pubertal Irradiation


ABSTRACT: Several lines of evidence indicate one's age at exposure to radiation strongly modifies the risk of radiation-induced breast cancer. We previously reported that rat mammary carcinomas induced by pre- and post-pubertal irradiation have distinct gene expression patterns, but the changes underlying these differences have not yet been characterized. The aim of this investigation was to see if differences in CpG DNA methylation were responsible for the differences in gene expression between age at exposure groups observed in our previous study.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE62383 | GEO | 2016/10/11

SECONDARY ACCESSION(S): PRJNA263958

REPOSITORIES: GEO

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