Effects of RUNX1 knockdown in AR signaling

ABSTRACT: Prostate cancer is the most common cancer in men and AR downstream signalings promote prostate cancer cell proliferation. We identified RUNX1 is an androgen-regulated gene. In order to investigate the RUNX1 function in prostate cancer cells, we performed gene expression in AR-positive prostate cancer cell lines after siRUNX1 treatment. We also treated cells with vehicle or androgen to analyzed the effects of RUNX1 on AR function.

ORGANISM(S): Homo sapiens

PROVIDER: GSE62454 | GEO | 2014/10/18

SECONDARY ACCESSION(S): PRJNA264149

REPOSITORIES: GEO