Genomics

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Development of NUP98-HOXA9 gene expression signatures


ABSTRACT: To explore the molecular mechanisms induced by the leukemic fusion protein NUP98-HOXA9, we performed gene expression analysis of human hematopoietic progenitors and primary samples of patients that express NUP98-HOXA9. By combining these data with ChIP-seq results, we observed that the fusion protein is able to both activate and repress the expression of its target genes.

ORGANISM(S): Homo sapiens

PROVIDER: GSE62585 | GEO | 2016/12/31

SECONDARY ACCESSION(S): PRJNA264479

REPOSITORIES: GEO

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